Toxicity of amyloid beta peptides and the effect of α-lipoic acid in cellular and fruit fly models of Alzheimer’s disease = Amüloid beeta peptiidide toksilisus ning α-lipoehappe mõju Alzheimeri tõve rakulistes ja äädikakärbse mudelites
author
supervisor
statement of authorship
Kristel Metsla ; [supervisor: Peep Palumaa, co-supervisor: Vello Tõugu ; Tallinn University of Technology, School of Science, Department of Chemistry and Biotechnology]
type of dissertation
doktoritöö
university/scientific institution
Tallinna Tehnikaülikool
location of publication
Tallinn
publisher
year of publication
pages
112 p. : ill
series
Tallinn University of Technology. Doctoral thesis = Tallinna Tehnikaülikool. Doktoritöö ; 76/2025
subject term
subject of form
ISSN
2585-6898
2585-6901 (PDF)
ISBN
978-9916-80-388-2 (PDF)
978-9916-80-387-5
notes
Autori publikatsioonide nimekiri leheküljel 6
Bibliogr. lk. 36-60
Kokkuvõte eesti keeles
Kättesaadav ka võrguteavikuna
Autori CV inglise ja eesti keeles, lk. 111-112
Thesis (Ph.D. in Gene Technology) : Tallinn University of Technology, 2025
url
Open Access
Open Access
scientific publication
teaduspublikatsioon
classifier
TalTech department
language
inglise
- Toxicity of amyloid-β peptides varies depending on differentiation route of SH-SY5Y cells
- α-Lipoic acid has the potential to normalize copper metabolism, which is dysregulated in Alzheimer’s disease
- In situ fibrillizing amyloid-beta 1-42 induces neurite degeneration and apoptosis of differentiated SH-SY5Y cells
Metsla, K. Toxicity of amyloid beta peptides and the effect of α-lipoic acid in cellular and fruit fly models of Alzheimer’s disease = Amüloid beeta peptiidide toksilisus ning α-lipoehappe mõju Alzheimeri tõve rakulistes ja äädikakärbse mudelites. Tallinn : TalTech Press, 2025. 112 p. : ill. (Tallinn University of Technology. Doctoral thesis = Tallinna Tehnikaülikool. Doktoritöö ; 76/2025).