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Amyloid-beta PET and CSF in an autopsy-confirmed cohortReimand, Juhan; Boon, Baayla D.C.; Collij, Lyduine E.; Teunissen, Charlotte E.; Rozemuller, Annemieke J.M.; Van Berckel, Bart N.M.; Scheltens, Philip; Ossenkoppele, Rik; Bouwman, FemkeAnnals of clinical and translational neurology2020 / p. 2150−2160 https://doi.org/10.1002/acn3.51195 Journal metrics at Scopus Article at Scopus Journal metrics at WOS Article at WOS

Antioxidative CXXC peptide motif from mesencephalic astrocyte-derived neurotrophic factor antagonizes programmed cell deathBožok, Valentina; Yu, Li-Ying; Palgi, Jaan; Arumäe, UrmasFrontiers in cell and developmental biology2018 / 15 p. : ill https://doi.org/10.3389/fcell.2018.00106 Journal metrics at Scopus Article at Scopus Journal metrics at WOS Article at WOS

Biotehnoloogilisi lähenemisi neurodegeneratiivsete haiguste raviksSaarma, MartEesti Arst2010 / 9, lk. 536-544 : ill

The CB1 cannabinoid receptor signals striatal neuroprotection via a PI3K/Akt/mTORC1/BDNF pathwayBlazquez, C.; Chiarlone, A.; Pruunsild, Priit; Timmusk, TõnisCell death and differentiation2015 / p. 1618-1629 : ill https://doi.org/10.1038/cdd.2015.11

Compound’s pre-screening of withania somnifera, Baccopa monnieri and centella asiatica extractsWitter, Steffi; Arju, Georg; Junusova, Marina; Kuhtinskaja, Maria; Samoson, Ago; Witter, Raiker; Vilu, RaivoJournal of biosciences and medicines2020 / p. 80-98 https://doi.org/10.4236/jbm.2020.89007

Coordination of zinc ions to the key proteins of neurodegenerative diseases: A[beeta], APP, [alfa]-synuclein and PrPTõugu, Vello; Palumaa, PeepCoordination chemistry reviews2012 / p. 2219-2224 : ill https://www.researchgate.net/publication/236131300_Coordination_of_zinc_ions_to_the_key_proteins_of_neurodegenerative_diseases_Ab_APP_a-synuclein_and_PrP

Cu(II) partially protects three histidine residues and the N-terminus of amyloid-β peptide from diethyl pyrocarbonate (DEPC) modificationFriedemann, Merlin; Tõugu, Vello; Palumaa, PeepFEBS Open Bio2020 / p. 1072-1081 https://doi.org/10.1002/2211-5463.12857 Journal metrics at Scopus Article at Scopus Journal metrics at WOS Article at WOS

CXXC peptide motif from mesencephalic astrocyte-derived neurotrophic factor (MANF) antagonizes apoptotic and necroptotic death and has anti-oxidant activityBozok, V.; Palgi, Jaan; Arumäe, UrmasNeurodegenerative diseases2015 / p. 1829 http://dx.doi.org/10.1159/000381736

Development of synthetic receptor-based sensors for detection of neurotrophic factor proteinsKidakova, Anna; Boroznjak, Roman; Reut, Jekaterina; Öpik, Andres; Sõritski, VitaliGraduate Student Symposium on Molecular Imprinting 2019, Berlin, Germany, August 28-30, 2019 : Symposium Programme and Book of Abstracts2019 / p. 31 https://drive.google.com/file/d/1zR0jNBFlayQ3AdKgX4YrCztpE00iSex-/view

Differential regulation of Bdnf expression in cortical neurons by class-selective histone deacetylase inhibitorsKoppel, Indrek; Timmusk, TõnisNeuropharmacology2013 / p. 106-115 : ill

Differential regulation of the BDNF gene in cortical and hippocampal neuronsEsvald, Eli-Eelika; Tuvikene, Jürgen; Moistus, Andra; Rannaste, Käthy; Kõomägi, Susann; Timmusk, TõnisJournal of neuroscience2022 / p. 9110-9128 https://doi.org/10.1523/JNEUROSCI.2535-21.2022 Journal metrics at Scopus Article at Scopus Journal metrics at WOS Article at WOS

Discordance between amyloid-β PET and CSF biomarkers : clinical and pathophysiological consequences = Amüloid-β staatuse vastuolu PET-uuringul ning liikvorianalüüsil : kliiniline ja patofüsioloogiline tähendusReimand, Juhan2021 https://doi.org/10.23658/taltech.15/2021 https://www.ester.ee/record=b5431268*est https://digikogu.taltech.ee/et/Item/d14a365f-fbfc-4595-923e-473262485fe2

Effect of methionine-35 oxidation on the aggregation of amyloid-β peptideFriedemann, Merlin; Helk, Eneken; Tiiman, Ann; Zovo, Kairit; Palumaa, Peep; Tõugu, VelloBiochemistry and biophysics reports2015 / p. 94-99 : ill http://dx.doi.org/10.1016/j.bbrep.2015.07.017

Electrochemical sensor based on molecularly imprinted polymer for rapid quantitative detection of brain-derived neurotrophic factorAyankojo, Akinrinade George; Boroznjak, Roman; Reut, Jekaterina; Tuvikene, Jürgen; Timmusk, Tõnis; Sõritski, VitaliSensors and Actuators B: Chemical2023 / art. 134656 https://doi.org/10.1016/j.snb.2023.134656

Electrochemical sensor based on moleculary imprinted polymers for label-free detection of neurotrophic factor protein [Online resource]Kidakova, Anna; Sõritski, Vitali; Reut, Jekaterina; Öpik, AndresTartu Ülikooli ASTRA projekt PER ASPERA : Funktsionaalsed materjalid ja tehnoloogiad : [4.-5. veebr. 2019, Tartu : teesid]2019 / 1 p http://fmtdk.ut.ee/teesid-2019/

Forkhead transcription factor FOXO3a levels are increased in Huntington disease because of overactivated positive autofeedback loopKannike, Kaja; Sepp, Mari; Zuccato, Chiara; Cattaneo, Elena; Timmusk, TõnisJournal of biological chemistry2014 / p. 32845-32857 : ill

Identification of two highly antigenic epitope markers predicting multiple sclerosis in optic neuritis patientsSadam, Helle; Pihlak, Arno; Jaago, Mariliis; Pupina, Nadežda; Rähni, Annika; Toots, Maarja; Vaheri, Antti; Nieminen, Janne K.; Siuko, Mika; Tienari, Pentti J.; Palm, KaiaEBioMedicine2021 / art. 103211, 8 p https://doi.org/10.1016/j.ebiom.2021.103211 Journal metrics at Scopus Article at Scopus Journal metrics at WOS Article at WOS

Identifying the role of co-aggregation of Alzheimer's amyloid-β with amorphous protein aggregates of non-amyloid proteinsWu, Jinming; Österlund, Nicklas; Wang, Hongzhi; Sternke-Hoffmann, R.; Pupart, Hegne; Ilag, Leopold L.; Gräslund, Astrid; Luo, JinghuiCell Reports Physical Science2022 / art. 101028 https://doi.org/10.1016/j.xcrp.2022.101028 Journal metrics at Scopus Article at Scopus Journal metrics at WOS Article at WOS

In vitro fibrillization of Alzheimer's amyloid-β peptide (1-42)Tiiman, Ann; Krištal, Jekaterina; Palumaa, Peep; Tõugu, VelloAIP advances2015 / p. 092401-1 - 092401-12 : ill http://dx.doi.org/10.1063/1.4921071

Isoform-specific reduction of the basic helix-Loop-helix transcription factor TCF4 levels in Huntington's diseaseNurm, Kaja; Sepp, Mari; Castany-Pladevall, Carla; Creus-Muncunill, Jordi; Tuvikene, Jürgen; Sirp, Alex; Vihma, Hanna; Blake, Derek J.; Perez-Navarro, Esther; Timmusk, TõniseNeuro2021 / 53 p. : ill https://doi.org/10.1523/ENEURO.0197-21.2021 Journal metrics at Scopus Article at Scopus Journal metrics at WOS Article at WOS

Lithium ions display weak interaction with amyloid-beta (Aβ) peptides and have minor effects on their aggregationBerntsson, Elina; Paul, Suman; Vosough, Faraz; Sholts, Sabrina B.; Jarvet, Jüri; Roos, Per M.; Barth, Andreas; Gräslund, Astrid; Wärmländer, Sebastian K. T. S.Acta biochimica Polonica2021 / p. 169-179 https://doi.org/10.18388/abp.2020_5493 Journal metrics at Scopus Article at Scopus Journal metrics at WOS Article at WOS

Mercury and Alzheimer’s disease: Hg(II) ions display specific binding to the amyloid-β peptide and hinder its fibrillizationWallin, Cecilia; Friedemann, Merlin; Sholts, Sabrina B.; Noormägi, Andra; Svantesson, Teodor; Järvet, Jüri; Roos, Per M.; Palumaa, Peep; Gräslund, Astrid; Wärmländer, Sebastian K.T.S.Biomolecules2020 / art. 44, 23 p. : ill https://doi.org/10.3390/biom10010044 Journal metrics at Scopus Article at Scopus Journal metrics at WOS Article at WOS

Metals in ALS TDP-43 pathologyKoski, Lassi; Ronnevi, Cecilia; Berntsson, Elina; Wärmländer, Sebastian K. T. S.; Roos, Per M.International Journal of Molecular Sciences2021 / Art. nr. 12193 https://doi.org/10.3390/ijms222212193 Journal metrics at Scopus Article at Scopus Journal metrics at WOS Article at WOS

Molecular profile of the rat peri-infarct region four days after stroke : Study with MANFTeppo, Jaakko; Vaikkinen, Anu; Stratoulias, Vassilis; Mätlik, Kert; Smolander, Olli-PekkaExperimental neurology2020 / art. 113288, 19 p. : ill https://doi.org/10.1016/j.expneurol.2020.113288 Journal metrics at Scopus Article at Scopus Journal metrics at WOS Article at WOS

Molecularly imprinted polymer-based SAW sensor for label-free detection of cerebral dopamine neurotrophic factor proteinKidakova, Anna; Boroznjak, Roman; Reut, Jekaterina; Öpik, Andres; Saarma, Mart; Sõritski, VitaliSensors and actuators B : chemical2020 / art. 127708, 8 p. : ill https://doi.org/10.1016/j.snb.2020.127708 Journal metrics at Scopus Article at Scopus Journal metrics at WOS Article at WOS

Monitoring of A-beta fibrillization using an improved fluorimetric methodKarafin, Ann; Palumaa, Peep; Tõugu, VelloNew Trends in Alzheimer and Parkinson Disorders : ADPD 20092009 / p. 255-259 https://www.etis.ee/Portal/Publications/Display/979eb21d-601b-4aa1-b941-121eff184407

Monitoring of amyloid-beta fibrillization using an improved fluorimetric method [Electronic resource]Karafin, Ann; Palumaa, Peep; Tõugu, VelloNeurodegenerative diseases2009 / S1, Alzheimer's and Parkinson's Diseases : Advances, Concepts and New Challenges, p. 799 [CD-ROM] https://www.etis.ee/Portal/Publications/Display/979eb21d-601b-4aa1-b941-121eff184407

Neurotrophic factors: new drugs for neurodegenerative diseasesSaarma, MartCollegium Internationale Neuro-Psychopharmacologicum (CINP) : final program and book of abstracts : Central/East European CINP Regional Meeting : Tallinn, Estonia, October 5-7, 20062006 / p. 68

Närvikasvufaktorid ja neurodegeneratiivsete haiguste ravi : kommentaar Põhjamaade teaduspreemia pälvinud tööleSaarma, MartTallinna Tehnikaülikooli aastaraamat 20092010 / lk. 199-204

Oxidation of Methionine-35 in Alzheimer's amyloid-beta peptide and the aggregation of the oxidized peptideFriedemann, Merlin; Helk, Eneken; Tiiman, Ann; Zovo, Kairit; Palumaa, Peep; Tõugu, VelloSpringerPlus2015 / p. 20, P13 http://dx.doi.org/10.1186/2193-1801-4-S1-P13

PET and CSF amyloid-β status are differently predicted by patient features: Information from discordant casesReimand, Juhan; Wilde, Arno de; Teunissen, Charlotte E.; Zwan, MarissaAlzheimer's Research & Therapy2019 / art. 100, 16 p. : ill https://doi.org/10.1186/s13195-019-0561-5 Journal metrics at Scopus Article at Scopus Journal metrics at WOS Article at WOS

Photo- and electropolymerization approaches for molecular imprinting of a neurotrophic factor proteinKidakova, Anna; Boroznjak, Roman; Reut, Jekaterina; Öpik, Andres; Sõritski, VitaliGSFMT Scientific Conference 2020 : Tallinn, February 4-5, 2020 : abstracts2020 / p. 43 http://fmtdk.ut.ee/wp-content/uploads/2020/01/GSFMT2020.pdf

Poststroke delivery of MANF promotes functional recovery in ratsMätlik, Kert; Anttila, Jenni E.; Kuan-Yin, Kuan-Yin; Arumäe, UrmasScience advances2018 / art. eaap8957 ; 8 p. : ill https://doi.org/10.1126/sciadv.aap8957 Journal metrics at Scopus Article at Scopus Journal metrics art WOS Article at WOS

Redox-active Cu(II)–Aβ causes substantial changes in axonal integrity in cultured cortical neurons in an oxidative-stress dependent mannerHowells, Claire; Saar, Katrina; Eaton, Emma; Ray, Shannon; Palumaa, PeepExperimental neurology2012 / p. 499-506 : ill https://www.sciencedirect.com/science/article/pii/S0014488612002373

Role of two sequence motifs of mesencephalic astrocyte-derived neurotrophic factor in its survival-promoting activityMätlik, Kert; Yu, Li-Ying; Eesmaa, Ave; Arumäe, UrmasCell death & disease2015 / art. e2032, p. 1-8 : ill http://dx.doi.org/10.1038/cddis.2015.371

Silmatorkamatu DNA jupp võib kujutada võtit ajuhaiguste leevendamiseksnovaator.err.ee2023 Silmatorkamatu DNA jupp võib kujutada võtit ajuhaiguste leevendamiseks Небольшой участок ДНК может стать ключом к лечению заболеваний мозга

Status epilepticus in 12-day-old rats leads to temporal lobe neurodegeneration and volume reduction : a histologic and MRI studyNairismägi, Jaak; Pitkänen, Asla; Kettunen, Mikko; Kauppinen, Risto; Kubova, HanaEpilepsia2006 / 3, p. 479-488 : ill https://pubmed.ncbi.nlm.nih.gov/16529609/

TAF4 controls differentiation of human neural progenitor cells through hTAF4-TAFH activityKazantseva, Jekaterina; Tints, Kairit; Neuman, Toomas; Palm, KaiaJournal of molecular neuroscience2015 / p. 160-166 : ill http://dx.doi.org/10.1007/s12031-014-0295-6

The glycine arginine-rich domain of the RNA-binding protein nucleolin regulates its subcellular localizationDoron-Mandel, Ella; Koppel, Indrek; Abraham, Ofri; Rishal, IdaThe EMBO Journal2021 / art. e107158 https://doi.org/10.15252/embj.2020107158 Journal metrics at Scopus Article at Scopus Journal metrics at WOS Article at WOS

Therapeutic potential of the endoplasmic reticulum located and secreted CDNF/MANF family of neurotrophic factors in Parkinson's diseaseVoutilainen, Merja H.; Arumäe, Urmas; Airavaara, Mikko; Saarma, MartFEBS letters2015 / p. 3739-3748 : ill http://dx.doi.org/10.1016/j.febslet.2015.09.031

Toxicity of amyloid beta 1-40 and 1-42 on SH-SY5Y cell lineKrištal, Jekaterina; Bragina, Olga; Metsla, Kristel; Palumaa, Peep; Tõugu, VelloSpringerPlus2015 / p. 21-22, P19 http://dx.doi.org/10.1186/2193-1801-4-S1-P19

Toxicity of amyloid-β peptides varies depending on differentiation route of SH-SY5Y cellsKrištal, Jekaterina; Metsla, Kristel; Bragina, Olga; Tõugu, Vello; Palumaa, PeepJournal of Alzheimer's disease2019 / p. 879−887 https://doi.org/10.3233/JAD-190705 Journal metrics at Scopus Article at Scopus Journal metrics at WOS Article at WOS

TTÜ geenitehnoloogid otsivad ravimit Alzheimeri tõvelePalumaa, Peep; Helme, KristiMente et Manu2013 / lk. 14-16 : fot

Wearable m-assessment system for neurological disease patientsKuusik, Alar; Alam, Muhammad Mahtab; Kask, Triin; Gross-Paju, KatrinProceedings : IEEE 4th World Forum on Internet of Things2018 / p. 201-206 : ill https://doi.org/10.1109/WF-IoT.2018.8355165

Why is amyloid-β PET requested after performing CSF biomarkers?Reimand, Juhan; Groot, Colin; Teunissen, Charlotte E.; Windhorst, Albert D.; Boellaard, Ronald; Barkhof, Frederike; Nazarenko, Sergei; van der Flier, Wiesje M.; Scheltens, Philip; Ossenkoppele, Rik; Bouwman, FemkeJournal of Alzheimer's disease2020 / p. 559-569 https://doi.org/10.3233/JAD-190836 Journal metrics at Scopus Article at Scopus Journal metrics at WOS Article at WOS