Molecular technology
TalTech priority area
Research classification (Frascati)
Head of the research group
Doctoral students
Keyword
Overview
Our group uses knowledge in syntheticc chemistry to molecularly design and test so-termednetworked molecules. These are a subset of multifunctional small-molecular-weight compoundsthat address the notions of chemical as well asbiological networks. In particular, we employ‘networked molecules’ to rationally build up well-organized molecular networks and successfully use themas electrocatalyst materials for variousapplications, incl. renewable energy and‘ligandless’ catalysis; disrupt and/or rewire biological networkswith a goal of inducing new intracellularinteractions and observing synergisticeffects.Such entities in their simplest form are heterobivalent constructs, however, we are lookingto install additional moieties that would helpextend their multifold performance.
Related projects
Related department
Teadusgrupiga seotud publikatsioonid
- Ávila-Bolívar, B., Cepitis, R., Alam, M., Starkov, P. et al. CO2 reduction to formate on an affordable bismuth metal-organic framework based catalyst // Journal of CO2 Utilization (2022) Vol. 59, art. 101937, 11 p.
https://doi.org/10.1016/j.jcou.2022.101937 - Ping, K., Alam, M., Kahnert, S. R., Bhadoria, R., Mere, A., Mikli, V., Käärik, M., Aruväli, J., Paiste, P., Kikas, A., Kisand, V., Järving, I., Leis, J., Kongi, N., Starkov, P. Multi-purpose heterogeneous catalyst material from an amorphous cobalt metal–organic framework // Materials advances (2021) vol. 2, p. 4009-4015.
https://doi.org/10.1039/D1MA00414J - Kazimova, N., Ping, K., Alam, M., Danilson, M., Merisalu, M., Aruväli, J., Paiste, P., Käärik, M., Mikli, V., Leis, J., Tammeveski, K., Starkov, P., Kongi, N. Shungite-derived graphene as a carbon support for bifunctional oxygen electrocatalysts // Journal of catalysis (2021) vol. 395, p. 178−187.
https://doi.org/10.1016/j.jcat.2021.01.004 - Ping, K., Brascinsky, A., Alam, M., Bhadoria, R., Mikli, V., Mere, A., Starkov, P. et al. Fused hybrid linkers for metal–organic framework-derived bifunctional oxygen electrocatalysts // ACS Applied Energy Materials (2020) vol. 3, 1, p. 152–157 : ill.
https://doi.org/10.1021/acsaem.9b02039 - Bhadoria, R., Ping, K., Lohk, C., Järving, I., Starkov, P. A phenotypic approach to probing cellular outcomes using heterobivalent constructs // Chemical Communications (2020) Vol. 56,30, p. 4216 - 4219.
https://doi.org/10.1039/c9cc09595k https://pubs.rsc.org/en/content/articlelanding/2020/cc/c9cc09595k - Ping, K., Alam, M., Käärik, M., Leis, J., Kongi, N., Järving, I., Starkov, P. Surveying iron–organic framework TAL-1-derived materials in ligandless heterogeneous oxidative catalytic transformations of alkylarenes // Synlett (2019) vol. 30, p. 1536–1540 : ill.
https://doi.org/10.1055/s-0037-1611877 - Kasak, L., Näks, M., Eek, P., Bhadoria, R., Starkov, P., Piirsoo, M. et al. Characterization of protein kinase ULK3 regulation by phosphorylation and inhibition by small molecule SU6668 // Biochemistry (2018) vol. 57, 37, p. 5456−5465.
https://doi.org/10.1021/acs.biochem.8b00356